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Explore the science behind hair loss and hair growth. Our in-depth articles cover topics ranging from natural remedies to pharmaceuticals to breakthroughs in hair loss science. Want to request an article topic? Contact us.

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Creatine: Does It Worsen Hair Loss? It Depends On The Hair Loss Type.
By Perfect Hair Health Team
Sep 27, 2024

Creatine: Does It Worsen Hair Loss? It Depends On The Hair Loss Type.

Creatine, a substance that supports energy production in the muscles and brain, is commonly used as a supplement to boost athletic performance. However, its potential link to hair loss has raised concerns, particularly due to its effect on dihydrotestosterone (DHT), a hormone associated with androge...
Can Progesterone Improve Hair Regrowth?
By Sarah King, PhD
Sep 18, 2024

Can Progesterone Improve Hair Regrowth?

Progesterone is a hormone that plays a vital role in female reproductive health. Deficiencies in progesterone have been linked to hair thinning, particularly in conditions like female pattern hair loss (FPHL) and postpartum telogen effluvium (PPTE). While natural progesterone seems to have 5-alpha-r...
HMI-115: What We Know So Far
By Sarah King, PhD
May 9, 2024

HMI-115: What We Know So Far

HMI-115 lowers prolactin levels and is currently in clinical trials for the treatment of androgenic alopecia (AGA). Internal, non-peer-reviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in ...
Turmeric (Curcumin) For Hair Regrowth? Big Claims, Limited Data
By Sarah King, PhD
Apr 19, 2024

Turmeric (Curcumin) For Hair Regrowth? Big Claims, Limited Data

Petri dish (i.e., in vitro) studies suggest that turmeric and its active constituent, curcumin, might decrease cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and nuclear factor kappa beta (NF-κB). Since these pathways and proteins share pathologic overlap with certain hair loss di...
EGCG: Does This Polyphenol Regrow Hair? | A Scientific Analysis
By Sarah King, PhD
Apr 11, 2024

EGCG: Does This Polyphenol Regrow Hair? | A Scientific Analysis

Epigallocatechin gallate (EGCG) is a popular ingredient found in hair growth supplements, serums, & topicals. Unfortunately, there’s little clinical data showing it can regrow hair in humans, and at higher doses, it might be toxic. On the one hand, in vitro studies suggest EGCG has 5-alpha...
Nourkrin® Review: Can Proteoglycans Actually Reverse Hair Loss?
By Sarah King, PhD
Apr 11, 2024

Nourkrin® Review: Can Proteoglycans Actually Reverse Hair Loss?

Nourkrin® markets its supplements as a “natural approach to hair loss”. The company differentiates itself with Marilex®: a “bioactive proteoglycan formula”. Three human studies suggest Nourkrin® products are effective at regrowing hair. Upon further investigation, each study ...
Harklinikken Extract: Uncovering The Real Evidence
By Sarah King, PhD
Apr 4, 2024

Harklinikken Extract: Uncovering The Real Evidence

Harklinikken Extract is a hair growth serum marketed to men & women with hair loss. Harklinikken keeps secret the full list of ingredients inside Extract. Of the ingredients that are disclosed, there is incredibly limited clinical evidence supporting their use in treating hair loss. Despite this...
Stinging Nettle For Hair Loss: Real vs. Perceived Benefits
By Perfect Hair Health Team
Apr 15, 2022

Stinging Nettle For Hair Loss: Real vs. Perceived Benefits

Stinging nettle is a popular natural remedy for hair loss. Unfortunately, quality studies on stinging nettle (and its effects on hair growth) are scarce. Most marketers selling stingle nettle relying almost exclusively on petri dish studies and mouse models to suggest it may have some hair-promoting...
Calcium’s Role In Hair Loss? It’s Complicated.
By Perfect Hair Health Team
Oct 20, 2020

Calcium’s Role In Hair Loss? It’s Complicated.

Calcium imbalances are linked to hair loss, with caveats. Low calcium and hair loss is seen in women with polycystic ovarian syndrome. High calcium and hair loss is reported in people with hyperparathyroidism. But in both cases, the calcium imbalances are consequences of the underlying conditions, n...
Vitamin B12, Hair Loss, & Methylation: Does This Vitamin Improve Hair Growth?
By Perfect Hair Health Team
Sep 16, 2020

Vitamin B12, Hair Loss, & Methylation: Does This Vitamin Improve Hair Growth?

Does vitamin B12 help regrow hair? Mechanistically, a lot of evidence suggests yes: vitamin B12 is important for DNA synthesis, hemoglobin production, and methylation – all of which play a role in healthy hair growth. Unfortunately, studies also show that people with and without hair loss have simil...

Stop guessing which hair loss
treatments actually work

Instead, just read our cheat sheet

You’ll get the facts on nine “natural” and “conventional” hair loss treatments: how they work, how much hair they’ll regrow, their limitations, and what their marketers don’t want you know.