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Explore the science behind hair loss and hair growth. Our in-depth articles cover topics ranging from natural remedies to pharmaceuticals to breakthroughs in hair loss science. Want to request an article topic? Contact us.

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Does Retinoic Acid (Tretinoin) Improve Hair Growth From Minoxidil?
By Sarah King, PhD
May 5, 2025

Does Retinoic Acid (Tretinoin) Improve Hair Growth From Minoxidil?

Retinoic acid, a biologically active form of vitamin A, has long been known for its role in skin health, but could it also help with hair loss? In this article, we explore the science behind retinoic acid and its derivative tretinoin, their effects on hair follicle stem cells, and whether clinical s...
Scalp Psoriasis: Symptoms, Causes, and Effects on Hair Loss
By Sarah King, PhD
Mar 25, 2025

Scalp Psoriasis: Symptoms, Causes, and Effects on Hair Loss

Scalp psoriasis goes beyond surface-level flaking; it’s a chronic autoimmune condition driven by genetic and immune system factors. From thick plaques and itching to potential hair loss, it can seriously impact daily life. Curious about what causes it, how to tell it apart from similar conditions, a...
Hair Loss Breakthroughs or Media Hype? Stem Cell Secretome Treatments
By Sarah King, PhD
Mar 4, 2025

Hair Loss Breakthroughs or Media Hype? Stem Cell Secretome Treatments

Stem cell secretome treatments are making headlines as the next big breakthrough in hair regrowth—but do they really work? While the science behind exosomes and growth factors sounds promising, media hype often overshadows the need for rigorous clinical trials. Curious about the real evidence behind...
Minoxidil Side Effects: Everything You Need To Know
By Sarah King, PhD
Feb 6, 2025

Minoxidil Side Effects: Everything You Need To Know

Minoxidil is an FDA-approved treatment for androgenic alopecia, but its use can come with side effects – from mild scalp irritation to cardiovascular risks. This comprehensive guide assess common and rare side effects from topical minoxidil and oral minoxidil – along with mitigation strategies....
Burdock Root For Hair Loss? A Look Into The Evidence
By Ben Fletcher, PhD
Jan 13, 2025

Burdock Root For Hair Loss? A Look Into The Evidence

Burdock root, derived from the plant Arctium lappa, has long been used in traditional medicine for its purported anti-inflammatory, antimicrobial, and antioxidant properties. In recent years, it has been included in natural hair loss treatments, with claims that it promotes hair growth. Some studies...
Which Vitamin Deficiences Can Cause Hair Loss?
By Sarah King, PhD
Dec 11, 2024

Which Vitamin Deficiences Can Cause Hair Loss?

Hair loss is a complex issue influenced by various factors, including vitamin deficiencies. We explored the impact (or lack thereof) of deficiencies in five vitamins – Vitamin D, Biotin, Vitamin B12, Vitamin E, and Vitamin A – on hair health and whether supplementation can aid hair regrowth. While d...
Creatine: Does It Worsen Hair Loss? It Depends On The Hair Loss Type. – 2025 Update
By Sarah King, PhD
Sep 27, 2024

Creatine: Does It Worsen Hair Loss? It Depends On The Hair Loss Type. – 2025 Update

Creatine, a substance that supports energy production in the muscles and brain, is commonly used as a supplement to boost athletic performance. However, its potential link to hair loss has raised concerns, particularly due to its effect on dihydrotestosterone (DHT), a hormone associated with androge...
Can Progesterone Improve Hair Regrowth?
By Sarah King, PhD
Sep 18, 2024

Can Progesterone Improve Hair Regrowth?

Progesterone is a hormone that plays a vital role in female reproductive health. Deficiencies in progesterone have been linked to hair thinning, particularly in conditions like female pattern hair loss (FPHL) and postpartum telogen effluvium (PPTE). While natural progesterone seems to have 5-alpha-r...
HMI-115: What We Know So Far
By Sarah King, PhD
May 9, 2024

HMI-115: What We Know So Far

HMI-115 lowers prolactin levels and is currently in clinical trials for the treatment of androgenic alopecia (AGA). Internal, non-peer-reviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in ...
Turmeric (Curcumin) For Hair Regrowth? Big Claims, Limited Data
By Sarah King, PhD
Apr 19, 2024

Turmeric (Curcumin) For Hair Regrowth? Big Claims, Limited Data

Petri dish (i.e., in vitro) studies suggest that turmeric and its active constituent, curcumin, might decrease cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and nuclear factor kappa beta (NF-κB). Since these pathways and proteins share pathologic overlap with certain hair loss di...

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You’ll get the facts on nine “natural” and “conventional” hair loss treatments: how they work, how much hair they’ll regrow, their limitations, and what their marketers don’t want you know.