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Explore the science behind hair loss and hair growth. Our in-depth articles cover topics ranging from natural remedies to pharmaceuticals to breakthroughs in hair loss science. Want to request an article topic? Contact us.

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Switching From Finasteride to Dutasteride
By Sophie Grice, PhD
Jan 13, 2026

Switching From Finasteride to Dutasteride

Switching from finasteride to dutasteride is often framed as a simple upgrade or downgrade. In reality, each switch changes not only DHT suppression but also exposure patterns, timelines for results, washout dynamics, and evidence quality. This article breaks down realistic switching scenarios, oral...
Does Finasteride Lower Testosterone?
By Catherine Kennedy, PhD
Jan 12, 2026

Does Finasteride Lower Testosterone?

Finasteride’s reputation for affecting hormones has led many to assume it suppresses testosterone, but the biology is far more nuanced. In this article, we unpack what happens to testosterone when DHT is inhibited, why levels often rise instead of fall, and how this squares with the sexual side effe...
Saw Palmetto Shampoo: Is It Effective for Hair Loss?
By Cassie Hopton, PhD
Jan 12, 2026

Saw Palmetto Shampoo: Is It Effective for Hair Loss?

Saw palmetto is hailed as a natural hair loss treatment, promising hair growth and strength. It is incorporated into all manner of hair loss products, including shampoos. But is the hype backed by science? This article dissects the science of saw palmetto as a hair growth ingredient, as well as sham...
Switching From Topical Minoxidil To Oral Minoxidil
By Michael Williams, PhD
Jan 12, 2026

Switching From Topical Minoxidil To Oral Minoxidil

Thinking about switching from topical to oral minoxidil, or back again? Changing your approach to hair loss can significantly improve your results, but changing treatment can also be a gamble that sets back progress. We break down what the evidence actually shows, when you might want to consider swi...
Does Spironolactone Cause Weight Gain?
By Cassie Hopton, PhD
Jan 12, 2026

Does Spironolactone Cause Weight Gain?

Spironolactone is a popular off-label treatment for female pattern hair loss, but many users worry about gaining weight while taking it. This article breaks down how the medication works, what the research actually shows about weight changes, typical dosing for hair growth, and simple strategies to ...
RU58841 for Hair Loss: Is It Legit?
By Sophie Grice, PhD
Jan 9, 2026

RU58841 for Hair Loss: Is It Legit?

RU58841 is one of the most talked-about research chemicals in hair loss forums, and the anecdotes are often surprisingly positive. Mechanistically, it makes sense: block androgen receptors in the scalp so dihydrotestosterone (DHT) can’t trigger follicle miniaturization. But the problem is that the h...
Oral vs. Topical Minoxidil: What’s Better for Hair Loss?
By Michael Williams, PhD
Jan 9, 2026

Oral vs. Topical Minoxidil: What’s Better for Hair Loss?

Oral vs topical minoxidil for hair loss: which works better, and at what cost? We break down the evidence on effectiveness, safety, dosing, and real-world tradeoffs to help you choose the right option.

Finasteride vs. Dutasteride: The Ultimate Guide
By Michael Williams, PhD
Dec 31, 2025

Finasteride vs. Dutasteride: The Ultimate Guide

Finasteride and dutasteride are the two most powerful medications available for androgenetic alopecia, but choosing between them isn’t straightforward. We break down how these drugs truly compare across efficacy, side effects, oral versus topical use, and real-world decision-making, so you can deter...
10 Ways to Reduce the Side Effects of Finasteride
By Michael Williams, PhD
Dec 31, 2025

10 Ways to Reduce the Side Effects of Finasteride

Finasteride is one of the most effective treatments for male pattern hair loss, but side effects can happen. This evidence-based guide outlines 10 practical strategies to reduce or manage finasteride side effects, from dose and formulation adjustments to lifestyle considerations, while emphasizing w...
Oral vs. Topical Dutasteride: What Studies Show
By Michael Williams, PhD
Dec 17, 2025

Oral vs. Topical Dutasteride: What Studies Show

Oral dutasteride is one of the most effective treatments for androgenic alopecia, but its systemic hormone suppression raises safety concerns. Topical dutasteride is often promoted as a way to deliver similar scalp-level benefits with fewer side effects, but does the evidence support that claim? In ...

Stop guessing which hair loss
treatments actually work

Instead, just read our cheat sheet

You’ll get the facts on nine “natural” and “conventional” hair loss treatments: how they work, how much hair they’ll regrow, their limitations, and what their marketers don’t want you know.