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Explore the science behind hair loss and hair growth. Our in-depth articles cover topics ranging from natural remedies to pharmaceuticals to breakthroughs in hair loss science. Want to request an article topic? Contact us.

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Zinc Supplements For Hair Loss: A Hard Look Into The Science
By Sarah King, PhD
Apr 25, 2024

Zinc Supplements For Hair Loss: A Hard Look Into The Science

Zinc is a popular trace element found in hair growth supplements. Animal studies suggest that zinc is required for healthy hair cycling. Human studies suggest that zinc deficiencies can cause hair loss from telogen effluvium. One study found that zinc sulfate might help with non-descript hair loss i...
Topical Minoxidil for Hair Growth: Efficacy, Safety, and How to Enhance Results
By Sarah King, PhD
Jul 16, 2025

Topical Minoxidil for Hair Growth: Efficacy, Safety, and How to Enhance Results

Topical minoxidil is the most established over-the-counter treatment for hair loss, with decades of use behind its FDA approval. But how does it actually work, and what determines whether it will work for you? In this article, we explore the science behind topical minoxidil, its strengths and limita...
OS-01 Hair Review: Does It Live Up to the Hype?
By Sarah King, PhD
Jun 23, 2025

OS-01 Hair Review: Does It Live Up to the Hype?

Curious about OneSkin’s OS-01 scalp serum that’s all over your feed? It claims to combat hair thinning by targeting cellular senescence, essentially attempting to “rejuvenate” your follicles. In this deep dive, we break down what senescence actually is, how it affects hair loss, and whether the scie...
Can Intermittent Fasting Cause Hair Loss? A Look Into A New Study
By Sarah King, PhD
Jan 14, 2025

Can Intermittent Fasting Cause Hair Loss? A Look Into A New Study

Intermittent fasting has gained popularity for its potential health benefits, but recent research highlights its possible impact on hair health. Studies on mice and humans suggest that fasting-induced metabolic shifts can slow hair growth and weaken hair shafts by depleting activated hair follicle s...
Which Vitamin Deficiences Can Cause Hair Loss?
By Sarah King, PhD
Dec 11, 2024

Which Vitamin Deficiences Can Cause Hair Loss?

Hair loss is a complex issue influenced by various factors, including vitamin deficiencies. We explored the impact (or lack thereof) of deficiencies in five vitamins – Vitamin D, Biotin, Vitamin B12, Vitamin E, and Vitamin A – on hair health and whether supplementation can aid hair regrowth. While d...
Genetic Tests: A Breakthrough for Personalized Hair Loss Treatments?
By Perfect Hair Health Team
Nov 21, 2024

Genetic Tests: A Breakthrough for Personalized Hair Loss Treatments?

Genetic testing is trending in the hair loss industry. The premise? Our genes hold the secrets to better hair growth, and genetic tests can help hair loss sufferers unlock new levels of hair gains with customized treatments. It’s an enticing proposition, albeit one that holds little-to-no scie...
Creatine: Does It Worsen Hair Loss? It Depends On The Hair Loss Type. – 2025 Update
By Sarah King, PhD
Sep 27, 2024

Creatine: Does It Worsen Hair Loss? It Depends On The Hair Loss Type. – 2025 Update

Creatine, a substance that supports energy production in the muscles and brain, is commonly used as a supplement to boost athletic performance. However, its potential link to hair loss has raised concerns, particularly due to its effect on dihydrotestosterone (DHT), a hormone associated with androge...
BTD: Can This Gene Predict Regrowth From Biotin?
By Ben Fletcher, PhD
Sep 8, 2024

BTD: Can This Gene Predict Regrowth From Biotin?

The BTD gene, responsible for encoding the enzyme biotinidase, is crucial for biotin metabolism. Biotin, or vitamin B7, plays a significant role in hair health, and biotinidase deficiency—caused by BTD polymorphisms—can lead to hair loss conditions like alopecia. While some studies suggest that biot...
COL1A1: Can This Gene Predict Regrowth From Collagen Support?
By Ben Fletcher, PhD
Sep 4, 2024

COL1A1: Can This Gene Predict Regrowth From Collagen Support?

The COL1A1 gene, responsible for producing a key component of type 1 collagen, has been associated with hair growth and structure. Certain genetic variations in COL1A1 might affect the balance of collagen chains, potentially influencing hair loss and the response to treatments. However, the current ...
Pyrilutamide (KX-826): A Promising Future Treatment For Hair Loss?
By Sarah King, PhD
May 9, 2024

Pyrilutamide (KX-826): A Promising Future Treatment For Hair Loss?

Pyrilutamide, also known as KX-826, is an anti-androgen topical currently being tested for the treatment of androgenic alopecia (AGA). Initial studies suggested that pyrilutamide might help reverse hair loss. However, larger-scale clinical studies have found no significant differences in hair regrow...

Stop guessing which hair loss
treatments actually work

Instead, just read our cheat sheet

You’ll get the facts on nine “natural” and “conventional” hair loss treatments: how they work, how much hair they’ll regrow, their limitations, and what their marketers don’t want you know.