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Explore the science behind hair loss and hair growth. Our in-depth articles cover topics ranging from natural remedies to pharmaceuticals to breakthroughs in hair loss science. Want to request an article topic? Contact us.

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Burdock Root For Hair Loss? A Look Into The Evidence
By Ben Fletcher, PhD
Jan 13, 2025

Burdock Root For Hair Loss? A Look Into The Evidence

Burdock root, derived from the plant Arctium lappa, has long been used in traditional medicine for its purported anti-inflammatory, antimicrobial, and antioxidant properties. In recent years, it has been included in natural hair loss treatments, with claims that it promotes hair growth. Some studies...
Which Vitamin Deficiences Can Cause Hair Loss?
By Sarah King, PhD
Dec 11, 2024

Which Vitamin Deficiences Can Cause Hair Loss?

Hair loss is a complex issue influenced by various factors, including vitamin deficiencies. We explored the impact (or lack thereof) of deficiencies in five vitamins – Vitamin D, Biotin, Vitamin B12, Vitamin E, and Vitamin A – on hair health and whether supplementation can aid hair regrowth. While d...
Genetic Tests: A Breakthrough for Personalized Hair Loss Treatments?
By Perfect Hair Health Team
Nov 21, 2024

Genetic Tests: A Breakthrough for Personalized Hair Loss Treatments?

Genetic testing is trending in the hair loss industry. The premise? Our genes hold the secrets to better hair growth, and genetic tests can help hair loss sufferers unlock new levels of hair gains with customized treatments. It’s an enticing proposition, albeit one that holds little-to-no scie...
Creatine: Does It Worsen Hair Loss? It Depends On The Hair Loss Type. – 2025 Update
By Sarah King, PhD
Sep 27, 2024

Creatine: Does It Worsen Hair Loss? It Depends On The Hair Loss Type. – 2025 Update

Creatine, a substance that supports energy production in the muscles and brain, is commonly used as a supplement to boost athletic performance. However, its potential link to hair loss has raised concerns, particularly due to its effect on dihydrotestosterone (DHT), a hormone associated with androge...
BTD: Can This Gene Predict Regrowth From Biotin?
By Ben Fletcher, PhD
Sep 8, 2024

BTD: Can This Gene Predict Regrowth From Biotin?

The BTD gene, responsible for encoding the enzyme biotinidase, is crucial for biotin metabolism. Biotin, or vitamin B7, plays a significant role in hair health, and biotinidase deficiency—caused by BTD polymorphisms—can lead to hair loss conditions like alopecia. While some studies suggest that biot...
COL1A1: Can This Gene Predict Regrowth From Collagen Support?
By Ben Fletcher, PhD
Sep 4, 2024

COL1A1: Can This Gene Predict Regrowth From Collagen Support?

The COL1A1 gene, responsible for producing a key component of type 1 collagen, has been associated with hair growth and structure. Certain genetic variations in COL1A1 might affect the balance of collagen chains, potentially influencing hair loss and the response to treatments. However, the current ...
Pyrilutamide (KX-826): A Promising Future Treatment For Hair Loss?
By Sarah King, PhD
May 9, 2024

Pyrilutamide (KX-826): A Promising Future Treatment For Hair Loss?

Pyrilutamide, also known as KX-826, is an anti-androgen topical currently being tested for the treatment of androgenic alopecia (AGA). Initial studies suggested that pyrilutamide might help reverse hair loss. However, larger-scale clinical studies have found no significant differences in hair regrow...
Green Tea: Is It An Effective Hair Loss Treatment?
By Sarah King, PhD
May 2, 2024

Green Tea: Is It An Effective Hair Loss Treatment?

Green tea extract contains epigallocatechin gallate (EGCG) and many other compounds that allegedly improve hair growth. On the one hand, in vitro studies suggest that EGCG might inhibit hair follicle damage. On the other hand, human studies do not yet exist showing that green tea – as a supplement o...
Inositol: A Sugar That Supports Hair Growth? | Clinical Study Analysis
By Sarah King, PhD
Apr 25, 2024

Inositol: A Sugar That Supports Hair Growth? | Clinical Study Analysis

Inositol (in the form of myo-inositol or D-chiro-inositol) is found in many hair growth supplements. Clinical studies suggest inositol might normalize androgen levels in women with polycystic ovarian syndrome (PCOS). For these reasons, marketers often claim inositol can help regrow hair for those wi...
Turmeric (Curcumin) For Hair Regrowth? Big Claims, Limited Data
By Sarah King, PhD
Apr 19, 2024

Turmeric (Curcumin) For Hair Regrowth? Big Claims, Limited Data

Petri dish (i.e., in vitro) studies suggest that turmeric and its active constituent, curcumin, might decrease cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and nuclear factor kappa beta (NF-κB). Since these pathways and proteins share pathologic overlap with certain hair loss di...

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You’ll get the facts on nine “natural” and “conventional” hair loss treatments: how they work, how much hair they’ll regrow, their limitations, and what their marketers don’t want you know.