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Explore the science behind hair loss and hair growth. Our in-depth articles cover topics ranging from natural remedies to pharmaceuticals to breakthroughs in hair loss science. Want to request an article topic? Contact us.

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Japanese Knotweed For Hair Loss: A Scientific Analysis
By Sarah King, PhD
Apr 25, 2024

Japanese Knotweed For Hair Loss: A Scientific Analysis

Japanese knotweed contains resveratrol and apigenin. In vitro studies suggest these compounds have antioxidant, anti-inflammatory, and anti-aging properties. Marketers claim these compounds support hair regrowth. So can Japanese knotweed regrow hair? In this article, we review the scientific literat...
Why Am I Shedding After Microneedling?
By Perfect Hair Health Team
Apr 25, 2024

Why Am I Shedding After Microneedling?

Temporary hair shedding is commonly reported after men & women start hair loss treatments like minoxidil. But is temporary hair shedding also normal when starting microneedling? On the one hand, microneedling induces acute inflammation. A little inflammation might benefit hair growth, while too ...
Ritlecitinib (Litfulo™) For Alopecia Areata: Benefits, Risks, & Hair Growth Outcomes
By Sarah King, PhD
Apr 24, 2024

Ritlecitinib (Litfulo™) For Alopecia Areata: Benefits, Risks, & Hair Growth Outcomes

In a recent milestone, a drug called ritlecitinib (brand name Litfulo™) was approved for treating alopecia areata (AA) in adolescents and adults. But is there high quality evidence supporting ritlecitinib? What are the long-term safety risks? And if it works, does this (relatively) new medication re...
Pump BioGro™: A Topical For Hair Regrowth? | Scientific Analysis
By Sarah King, PhD
Apr 19, 2024

Pump BioGro™: A Topical For Hair Regrowth? | Scientific Analysis

Pump BioGro™ is a topical product marketed by Pump Haircare. Its makers claim that Pump BioGro™ is clinically proven to reduce hair shedding and promote hair growth by inhibiting fibroblast growth factor 5 (FGF5) – a growth factor that Pump Haircare suggests might negatively impact hair cycling. Dur...
What Happens If I Stop Microneedling?
By Sarah King, PhD
Apr 19, 2024

What Happens If I Stop Microneedling?

In general, treatments for hair loss are only effective as long as they are continued. However, limited data suggests that microneedling may exert its effects up to six months post-treatment (with or without minoxidil). In this article, we will dive into the research behind how long the positive hai...
Reparex (For Grey Hair): Does It Really Reverse Greying? | Scientific Analysis
By Sarah King, PhD
Apr 19, 2024

Reparex (For Grey Hair): Does It Really Reverse Greying? | Scientific Analysis

Reparex’s Against Grey Hair claims to “restore hair color naturally from the inside out”. During our company investigation, we found discrepancies between Reparex’s marketing claims and the mechanisms governing the graying process. We also found duplicative before-after photo...
Vitamin C (Ascorbic Acid) For Hair Regrowth: Fact vs. Fiction
By Sarah King, PhD
Apr 19, 2024

Vitamin C (Ascorbic Acid) For Hair Regrowth: Fact vs. Fiction

Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that is naturally present in citrus fruits. Because humans lack an enzyme called gulonolactone oxidase, vitamin C must be taken up through the diet. The majority of evidence concerning vitamin C and its potential for hair growth is f...
Amino Acids To Treat Hair Loss? A Small Literature Review
By Richard Clayton, PhD
Apr 19, 2024

Amino Acids To Treat Hair Loss? A Small Literature Review

Amino acids are biomolecules and the building blocks of proteins. Marketers often misappropriate petri dish, animal, and small-scale human studies to suggest that the amino acids lysine, arginine, proline, & thiamine might help treat hair loss. But is this supported by clinical studies on humans...
Turmeric (Curcumin) For Hair Regrowth? Big Claims, Limited Data
By Sarah King, PhD
Apr 19, 2024

Turmeric (Curcumin) For Hair Regrowth? Big Claims, Limited Data

Petri dish (i.e., in vitro) studies suggest that turmeric and its active constituent, curcumin, might decrease cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and nuclear factor kappa beta (NF-κB). Since these pathways and proteins share pathologic overlap with certain hair loss di...
How To Identify How Fast You’re Losing Hair & Why This Matters
By Perfect Hair Health Team
Apr 19, 2024

How To Identify How Fast You’re Losing Hair & Why This Matters

On average, people with androgenic alopecia lose 5% hair volume per year. However, this rate of progression is just an average; some people lose hair much faster. Those with rapidly-progressing hair loss face higher opportunity costs for treatment failures, and therefore have less opportunity to exp...

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treatments actually work

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You’ll get the facts on nine “natural” and “conventional” hair loss treatments: how they work, how much hair they’ll regrow, their limitations, and what their marketers don’t want you know.