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What is it?
What is it?
What is it?
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Aenean scelerisque, nulla ut vulputate pretium, sapien velit volutpat ipsum, non mattis dui nulla tempus eros.
Parameter |
Inclusion Criteria |
Exclusion Criteria |
Patients | Patients of any age with hair loss | Patients with no hair loss disorder. |
Intervention | Oral finasteride as a standalone or adjunct therapy. | A study that doesn’t contain oral finasteride either as a standalone or adjunct therapy |
Comparator | Placebo and/or other therapies or baseline. | No comparator. |
Outcomes | No comparator.Primary Endpoints of phototrichogram, investigator, and/or patient assessments. | Any study not designed to adequately test for the standalone or additive effect of oral finasteride. |
Study Design | Prospective, randomized controlled trials | Literature reviews, non-human subjects, or ongoing clinical trials. |
Study | Participants | Design | Treatment | Results | Key Takeaway | Adverse Effects | EQ | |||||
Authors (year) | Sex | Hair Loss Type | Design | Dose | Usage | Duration | Endpoints | Hair Growth Assessments | Summary | Limitations | Adverse Effects | Jadad Score |
Liang et al. (2023) | n=120(F) Group 1: 40 Group 2: 40 Group 3: 40 | FPHL | Prospective, single-center, parallel-group, evaluator-blinded, randomized trial | Group 1: 5% MXT Group 2: 5% MX + 80-100 mg SPT Group 3: 5% topical MX + MN | Group 1: Once daily. Group 2: Once daily. Group 3: MXT once daily, alongside MN every 2 weeks. | 24 weeks | Dermascope evaluation, ultrasound biomicroscopy (UBM), physician's global assessment, and patient assessment. | Group 1: showed improvement at week 24 in hair density and shaft diameter. The effective rate was 55.27% at week 24. Group 2: The effective rate was 86.49% at week 24. Group 3: The effective rate was 95% at week 24. The degree of improvement of hair density at week 24 in Group 1 was less than in the latter two. | The combined therapies showed advantages in efficacy over 5% MXT alone. Group 3 showed significant improvement in most endpoints, including hair density, hair shaft, diameter, epidermal thickness, dermis thickness, follicle diameter, hair shedding score, and QoL score | Small sample size, exclusion of severe FPHL patients, and potential bias from unblinded treatments among the 3 groups. | Group 1: Facial hypertrichosis (n=4), trichomadesis aggravating (n=4), scalp pruritus (n=8), increased scurf (n=7), headache (n=1), palpitation (n=1), postural hypotension (n=1), urticaria (n=1). Group 2: facial hypertrichosis (n=5), trichomadesis aggravating (n=4), scalp pruritus (n=8), increased scurf (n=6), edema (n=1), headache (n=1), palpitation (n=3), hyperkalemia (n=1), menstrual disorder (n=15), urticaria (n=1) |
4
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Liang et al. (2023) | n=120(F) Group 1: 40 Group 2: 40 Group 3: 40 | FPHL | Prospective, single-center, parallel-group, evaluator-blinded, randomized trial | Group 1: 5% MXT Group 2: 5% MX + 80-100 mg SPT Group 3: 5% topical MX + MN | Group 1: Once daily. Group 2: Once daily. Group 3: MXT once daily, alongside MN every 2 weeks. | 24 weeks | Dermascope evaluation, ultrasound biomicroscopy (UBM), physician's global assessment, and patient assessment. | Group 1: showed improvement at week 24 in hair density and shaft diameter. The effective rate was 55.27% at week 24. Group 2: The effective rate was 86.49% at week 24. Group 3: The effective rate was 95% at week 24. The degree of improvement of hair density at week 24 in Group 1 was less than in the latter two. | The combined therapies showed advantages in efficacy over 5% MXT alone. Group 3 showed significant improvement in most endpoints, including hair density, hair shaft, diameter, epidermal thickness, dermis thickness, follicle diameter, hair shedding score, and QoL score | Small sample size, exclusion of severe FPHL patients, and potential bias from unblinded treatments among the 3 groups. | Group 1: Facial hypertrichosis (n=4), trichomadesis aggravating (n=4), scalp pruritus (n=8), increased scurf (n=7), headache (n=1), palpitation (n=1), postural hypotension (n=1), urticaria (n=1). Group 2: facial hypertrichosis (n=5), trichomadesis aggravating (n=4), scalp pruritus (n=8), increased scurf (n=6), edema (n=1), headache (n=1), palpitation (n=3), hyperkalemia (n=1), menstrual disorder (n=15), urticaria (n=1) |
4
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Explore the science behind hair loss and hair growth. Our in-depth articles cover topics ranging from natural remedies to pharmaceuticals to breakthroughs in hair loss science. Want to request an article topic? Contact us.
HMI-115 lowers prolactin levels and is currently in clinical trials for the treatment of androgenic alopecia (AGA). Internal, non-peer-reviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …
HMI-115 lowers prolactin levels and is currently in clinical trials for the treatment of androgenic alopecia (AGA). Internal, non-peer-reviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …
HMI-115 lowers prolactin levels and is currently in clinical trials for the treatment of androgenic alopecia (AGA). Internal, non-peer-reviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …
HMI-115 lowers prolactin levels and is currently in clinical trials for the treatment of androgenic alopecia (AGA). Internal, non-peer-reviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …
eviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …
What is it?
What is it?
What is it?
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Aenean scelerisque, nulla ut vulputate pretium, sapien velit volutpat ipsum, non mattis dui nulla tempus eros.
Parameter |
Inclusion Criteria |
Exclusion Criteria |
Patients | Patients of any age with hair loss | Patients with no hair loss disorder. |
Intervention | Oral finasteride as a standalone or adjunct therapy. | A study that doesn’t contain oral finasteride either as a standalone or adjunct therapy |
Comparator | Placebo and/or other therapies or baseline. | No comparator. |
Outcomes | No comparator.Primary Endpoints of phototrichogram, investigator, and/or patient assessments. | Any study not designed to adequately test for the standalone or additive effect of oral finasteride. |
Study Design | Prospective, randomized controlled trials | Literature reviews, non-human subjects, or ongoing clinical trials. |
Study | Participants | Design | Treatment | Results | Key Takeaway | Adverse Effects | EQ | |||||
Authors (year) | Sex | Hair Loss Type | Design | Dose | Usage | Duration | Endpoints | Hair Growth Assessments | Summary | Limitations | Adverse Effects | Jadad Score |
Liang et al. (2023) | n=120(F) Group 1: 40 Group 2: 40 Group 3: 40 | FPHL | Prospective, single-center, parallel-group, evaluator-blinded, randomized trial | Group 1: 5% MXT Group 2: 5% MX + 80-100 mg SPT Group 3: 5% topical MX + MN | Group 1: Once daily. Group 2: Once daily. Group 3: MXT once daily, alongside MN every 2 weeks. | 24 weeks | Dermascope evaluation, ultrasound biomicroscopy (UBM), physician's global assessment, and patient assessment. | Group 1: showed improvement at week 24 in hair density and shaft diameter. The effective rate was 55.27% at week 24. Group 2: The effective rate was 86.49% at week 24. Group 3: The effective rate was 95% at week 24. The degree of improvement of hair density at week 24 in Group 1 was less than in the latter two. | The combined therapies showed advantages in efficacy over 5% MXT alone. Group 3 showed significant improvement in most endpoints, including hair density, hair shaft, diameter, epidermal thickness, dermis thickness, follicle diameter, hair shedding score, and QoL score | Small sample size, exclusion of severe FPHL patients, and potential bias from unblinded treatments among the 3 groups. | Group 1: Facial hypertrichosis (n=4), trichomadesis aggravating (n=4), scalp pruritus (n=8), increased scurf (n=7), headache (n=1), palpitation (n=1), postural hypotension (n=1), urticaria (n=1). Group 2: facial hypertrichosis (n=5), trichomadesis aggravating (n=4), scalp pruritus (n=8), increased scurf (n=6), edema (n=1), headache (n=1), palpitation (n=3), hyperkalemia (n=1), menstrual disorder (n=15), urticaria (n=1) |
4
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Liang et al. (2023) | n=120(F) Group 1: 40 Group 2: 40 Group 3: 40 | FPHL | Prospective, single-center, parallel-group, evaluator-blinded, randomized trial | Group 1: 5% MXT Group 2: 5% MX + 80-100 mg SPT Group 3: 5% topical MX + MN | Group 1: Once daily. Group 2: Once daily. Group 3: MXT once daily, alongside MN every 2 weeks. | 24 weeks | Dermascope evaluation, ultrasound biomicroscopy (UBM), physician's global assessment, and patient assessment. | Group 1: showed improvement at week 24 in hair density and shaft diameter. The effective rate was 55.27% at week 24. Group 2: The effective rate was 86.49% at week 24. Group 3: The effective rate was 95% at week 24. The degree of improvement of hair density at week 24 in Group 1 was less than in the latter two. | The combined therapies showed advantages in efficacy over 5% MXT alone. Group 3 showed significant improvement in most endpoints, including hair density, hair shaft, diameter, epidermal thickness, dermis thickness, follicle diameter, hair shedding score, and QoL score | Small sample size, exclusion of severe FPHL patients, and potential bias from unblinded treatments among the 3 groups. | Group 1: Facial hypertrichosis (n=4), trichomadesis aggravating (n=4), scalp pruritus (n=8), increased scurf (n=7), headache (n=1), palpitation (n=1), postural hypotension (n=1), urticaria (n=1). Group 2: facial hypertrichosis (n=5), trichomadesis aggravating (n=4), scalp pruritus (n=8), increased scurf (n=6), edema (n=1), headache (n=1), palpitation (n=3), hyperkalemia (n=1), menstrual disorder (n=15), urticaria (n=1) |
4
|
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Aenean scelerisque, nulla ut vulputate pretium, sapien velit volutpat ipsum, non mattis dui nulla tempus eros.
HMI-115 lowers prolactin levels and is currently in clinical trials for the treatment of androgenic alopecia (AGA). Internal, non-peer-reviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …
HMI-115 lowers prolactin levels and is currently in clinical trials for the treatment of androgenic alopecia (AGA). Internal, non-peer-reviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …
HMI-115 lowers prolactin levels and is currently in clinical trials for the treatment of androgenic alopecia (AGA). Internal, non-peer-reviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …
HMI-115 lowers prolactin levels and is currently in clinical trials for the treatment of androgenic alopecia (AGA). Internal, non-peer-reviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …
eviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …
What is it?
What is it?
What is it?
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Aenean scelerisque, nulla ut vulputate pretium, sapien velit volutpat ipsum, non mattis dui nulla tempus eros.
Parameter |
Inclusion Criteria |
Exclusion Criteria |
Patients | Patients of any age with hair loss | Patients with no hair loss disorder. |
Intervention | Oral finasteride as a standalone or adjunct therapy. | A study that doesn’t contain oral finasteride either as a standalone or adjunct therapy |
Comparator | Placebo and/or other therapies or baseline. | No comparator. |
Outcomes | No comparator.Primary Endpoints of phototrichogram, investigator, and/or patient assessments. | Any study not designed to adequately test for the standalone or additive effect of oral finasteride. |
Study Design | Prospective, randomized controlled trials | Literature reviews, non-human subjects, or ongoing clinical trials. |
Study | Participants | Design | Treatment | Results | Key Takeaway | Adverse Effects | EQ | |||||
Authors (year) | Sex | Hair Loss Type | Design | Dose | Usage | Duration | Endpoints | Hair Growth Assessments | Summary | Limitations | Adverse Effects | Jadad Score |
Liang et al. (2023) | n=120(F) Group 1: 40 Group 2: 40 Group 3: 40 | FPHL | Prospective, single-center, parallel-group, evaluator-blinded, randomized trial | Group 1: 5% MXT Group 2: 5% MX + 80-100 mg SPT Group 3: 5% topical MX + MN | Group 1: Once daily. Group 2: Once daily. Group 3: MXT once daily, alongside MN every 2 weeks. | 24 weeks | Dermascope evaluation, ultrasound biomicroscopy (UBM), physician's global assessment, and patient assessment. | Group 1: showed improvement at week 24 in hair density and shaft diameter. The effective rate was 55.27% at week 24. Group 2: The effective rate was 86.49% at week 24. Group 3: The effective rate was 95% at week 24. The degree of improvement of hair density at week 24 in Group 1 was less than in the latter two. | The combined therapies showed advantages in efficacy over 5% MXT alone. Group 3 showed significant improvement in most endpoints, including hair density, hair shaft, diameter, epidermal thickness, dermis thickness, follicle diameter, hair shedding score, and QoL score | Small sample size, exclusion of severe FPHL patients, and potential bias from unblinded treatments among the 3 groups. | Group 1: Facial hypertrichosis (n=4), trichomadesis aggravating (n=4), scalp pruritus (n=8), increased scurf (n=7), headache (n=1), palpitation (n=1), postural hypotension (n=1), urticaria (n=1). Group 2: facial hypertrichosis (n=5), trichomadesis aggravating (n=4), scalp pruritus (n=8), increased scurf (n=6), edema (n=1), headache (n=1), palpitation (n=3), hyperkalemia (n=1), menstrual disorder (n=15), urticaria (n=1) |
4
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Liang et al. (2023) | n=120(F) Group 1: 40 Group 2: 40 Group 3: 40 | FPHL | Prospective, single-center, parallel-group, evaluator-blinded, randomized trial | Group 1: 5% MXT Group 2: 5% MX + 80-100 mg SPT Group 3: 5% topical MX + MN | Group 1: Once daily. Group 2: Once daily. Group 3: MXT once daily, alongside MN every 2 weeks. | 24 weeks | Dermascope evaluation, ultrasound biomicroscopy (UBM), physician's global assessment, and patient assessment. | Group 1: showed improvement at week 24 in hair density and shaft diameter. The effective rate was 55.27% at week 24. Group 2: The effective rate was 86.49% at week 24. Group 3: The effective rate was 95% at week 24. The degree of improvement of hair density at week 24 in Group 1 was less than in the latter two. | The combined therapies showed advantages in efficacy over 5% MXT alone. Group 3 showed significant improvement in most endpoints, including hair density, hair shaft, diameter, epidermal thickness, dermis thickness, follicle diameter, hair shedding score, and QoL score | Small sample size, exclusion of severe FPHL patients, and potential bias from unblinded treatments among the 3 groups. | Group 1: Facial hypertrichosis (n=4), trichomadesis aggravating (n=4), scalp pruritus (n=8), increased scurf (n=7), headache (n=1), palpitation (n=1), postural hypotension (n=1), urticaria (n=1). Group 2: facial hypertrichosis (n=5), trichomadesis aggravating (n=4), scalp pruritus (n=8), increased scurf (n=6), edema (n=1), headache (n=1), palpitation (n=3), hyperkalemia (n=1), menstrual disorder (n=15), urticaria (n=1) |
4
|
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Aenean scelerisque, nulla ut vulputate pretium, sapien velit volutpat ipsum, non mattis dui nulla tempus eros.
HMI-115 lowers prolactin levels and is currently in clinical trials for the treatment of androgenic alopecia (AGA). Internal, non-peer-reviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …
HMI-115 lowers prolactin levels and is currently in clinical trials for the treatment of androgenic alopecia (AGA). Internal, non-peer-reviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …
HMI-115 lowers prolactin levels and is currently in clinical trials for the treatment of androgenic alopecia (AGA). Internal, non-peer-reviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …
HMI-115 lowers prolactin levels and is currently in clinical trials for the treatment of androgenic alopecia (AGA). Internal, non-peer-reviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …
eviewed research suggests that HMI-115 may promote hair regrowth in monkeys. Anecdotes from its phase I trials in humans imply that HMI-115 may also regrow hair in men with AGA. But is this the whole story? In …