5 Ways to Prevent Hair Loss While Taking Testosterone

Article Summary

Testosterone replacement therapy can transform energy, mood, and libido, but it often comes with an unwelcome side effect: accelerated hair loss. This guide breaks down the science of how TRT ramps up DHT and outlines five evidence-based strategies to protect your hair without sacrificing hormonal benefits. You’ll see exactly how oral meds, topicals, growth boosters, and OTC support can be combined into a tailored plan. Learn how to keep both your testosterone and your hairline in a healthy place long term.

Full Article

Testosterone replacement therapy (TRT) can be a life-changing treatment for many men, restoring healthy hormone levels and renewing vitality after declines associated with low testosterone. However, many encounter a harsh irony: the same treatment that revitalizes them may also lead to accelerated hair loss, known as androgenetic alopecia (AGA). This frustrating dilemma can compel some men to choose between their appearance and their health. 

Why do TRT patients often experience hair thinning just months into treatment? The culprit is testosterone’s conversion to DHT, the hormone that drives male pattern hair loss. Fortunately, new developments in comprehensive care address the testosterone-to-hair-loss pathway, allowing men to enjoy both hormone optimization and healthy hair. These clinically rigorous, customizable, and medically supervised treatments eliminate the either-or paradox.

Perfect Hair Health’s PhD experts have teamed up with Ulo, a leader in men’s wellness and hair care, to share five evidence-based techniques for preserving hair while on TRT. With Ulo’s unique expertise at the intersection of hormone optimization and hair restoration, patients gain access to solutions that are both proven and personalized.

Read on to learn how Ulo can help you maintain both hormonal health and hair density.

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The Science of Testosterone and Hair Loss 

Before exploring solutions, we will briefly explain the science behind TRT and hair loss, including relevant medical research that supports prevention-based strategies for preserving hair during TRT.

Testosterone Metabolism and DHT Formation

To understand the link between TRT and hair loss, we turn to the molecular process that converts testosterone into dihydrotestosterone (DHT), the hormone that causes follicular degradation and balding. Two types of 5α-reductase enzymes are responsible for deriving DHT from testosterone: Type I (primarily located in the skin and sebaceous glands) and Type II (mainly located in the hair follicles of the crown and temporal regions).^[1]Owecka, B., Tomaszewska, A., Dobrzeniecki, K., Owecki, M. (2024). The Hormonal Background of Hair Loss in Non-Scarring Alopecias. Biomedicines. 12(3). 513. Available at: … Continue reading

Androgenetic alopecia (AGA) can occur naturally in susceptible individuals, whose hair follicles have high concentrations of androgen receptors and 5α-reductase enzymes. However, adding exogenous T through TRT can expedite this process. TRT’s elevation of testosterone levels can raise DHT to two or three times higher than starting levels, depending on the dosage and mode of application. The conversion of T to DHT is especially prevalent in the crown and temporal areas of the scalp, where it causes hair thinning and loss.^[2]Owecka, B., Tomaszewska, A., Dobrzeniecki, K., Owecki, M. (2024). The Hormonal Background of Hair Loss in Non-Scarring Alopecias. Biomedicines. 12(3). 513. Available at: … Continue reading,^[3]Stocks, B., Asempa, O. (2025). Does testosterone replacement therapy cause hair loss? Baylor College of Medicine. Available at: … Continue reading

Genetic predisposition plays a significant role, as variations in androgen receptor genes determine individual sensitivity to DHT. This explains why patients on identical TRT regimens can experience varying levels of hair loss, with some experiencing dramatic loss and others experiencing little or no effect. In those with hereditary androgen sensitivity, the hair follicles respond poorly to even slight elevations in local DHT levels on the scalp.^[4]Owecka, B., Tomaszewska, A., Dobrzeniecki, K., Owecki, M. (2024). The Hormonal Background of Hair Loss in Non-Scarring Alopecias. Biomedicines. 12(3). 513. Available at: … Continue reading

Why TRT Accelerates Pattern Hair Loss

As previously noted, TRT increases testosterone and leads to higher levels of its derivative hormone, DHT, which binds to hair follicles and causes hair thinning and loss in genetically susceptible men. Spikes in DHT and associated hair loss can occur even with moderate TRT, as raising testosterone into the normal range can represent a significant increase from severe deficiency.^[5]Borst, S.E., Shuster, J.J., Zou, B., Ye, F., Jia, H., Wokhlu, A., Yarrow, J.F. (2014). Cardiovascular risks and elevation of serum DHT vary by route of testosterone administration: a systemic review … Continue reading  

Episodic TRT protocols like weekly injections can create testosterone peaks over 1,200 ng/dL for up to 48 hours after injection, leading to surges in scalp DHT production during these windows. Such DHT spikes can damage the follicles and contribute to rapid hair loss.^[6]Stocks, B., Asempa, O. (2025). Does testosterone replacement therapy cause hair loss? Baylor College of Medicine. Available at: … Continue reading,^[7]Shoskes, J.J., Wilson, M.K., Spinner, M.L. (2016). Pharmacology of testosterone replacement therapy preparations. Translational Andrology and Urology. 5(6). 834-843. Available at: … Continue reading 

Disruption of hair follicle cycles can begin in the first 3-6 weeks of TRT. However, noticeable hair loss typically doesn’t emerge for several months, as early damage is concealed by hair growth cycles. Studies suggest higher TRT doses correlate with more rapid hair loss in susceptible patients.^[8]Saad, F., Aversa, A., Isidori, A.M., Zafalon, L., Zitzmann, M., Gooren, L. (2011). Onset of effects of testosterone treatment and time span until maximum effects are achieved. European Journal of … Continue reading,^[9]Fu, D., Huang, J., Li, K., Chen, Y., He, Y., Sun, Y., Guo, Y., Du, L., Qu, Q., Miao, Y., Hu, Z. (2021). Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 … Continue reading

Balancing Hormonal Benefits with Hair Protection

Although DHT can harm the hair follicles, it plays a vital role in various biological processes, including sexual function, bone mineralization, and muscle development. Therefore, the aim of hair loss treatment during TRT is not to eliminate the hormone. Rather, the therapeutic goal is to lower DHT to a level that minimizes follicular damage while preserving systemic functions. Striking this balance in individuals often requires sophisticated strategies that exceed standardized DHT suppression protocols.^[10]Owecka, B., Tomaszewska, A., Dobrzeniecki, K., Owecki, M. (2024). The Hormonal Background of Hair Loss in Non-Scarring Alopecias. Biomedicines. 12(3). 513. Available at: … Continue reading 

While some patients may be tempted to terminate TRT to protect their hair, research findings support a more measured approach that takes TRT’s broader benefits into account. Patients who elect to stop taking testosterone for hair preservation may experience a return of detrimental symptoms: sexual dysfunction, depression, fatigue, muscle loss, and more. The psychological and physiological impacts of low T can outweigh cosmetic concerns.

Given these considerations, practitioners advise strategic early intervention over reactionary care, as hair restoration becomes much more challenging after considerable follicular shrinkage. Early discussion with healthcare providers about hair preservation strategies helps maintain hair health throughout the hormone optimization process.^[11]Owecka, B., Tomaszewska, A., Dobrzeniecki, K., Owecki, M. (2024). The Hormonal Background of Hair Loss in Non-Scarring Alopecias. Biomedicines. 12(3). 513. Available at: … Continue reading 

With the science behind TRT and hair loss clear, let’s look at the latest, evidence-based ways patients can protect their hair.

Expert Solutions for TRT-Related Hair Loss

Hair loss associated with TRT often has distinct features, like episodic spikes in testosterone and DHT conversion rates. Although conventional hair loss interventions can be useful, protocols may benefit from personalization according to TRT regimens.

Ulo is a unique provider due to its innovative hair loss treatments and dual expertise in both hair restoration and hormone optimization. This combined clinical experience enables them to tailor treatments to individual patient needs, such as timing factors and treatment responses specific to TRT. All Ulo treatment protocols are physician-crafted and include close follow-up care to monitor for side effects and make adjustments as needed.

Treatment Options Overview

This overview outlines Ulo’s comprehensive strategy for hair loss intervention, from advanced prescription formulas to targeted nutritional support. All offerings are transparently priced with customizable features to account for TRT-related factors and individual patient considerations.

Product Category	Mechanism of Action	Delivery Method	Formula Details	Price
Oral Medications	Systemic 5α-reductase inhibition and vasodilation	Oral capsule, tablet, or softgel	Finasteride, dutasteride, and minoxidil for systemic DHT blocking and growth stimulation	$24-65/month
Topical Finasteride	Localized Type II 5α-reductase inhibition with minimal systemic exposure	Solution	Concentration range (0.005%-0.2%); customizable adjuvants; irritant-free	$64+/month
Topical Dutasteride	Localized dual enzyme (Types I & II) inhibition for maximum scalp DHT suppression	Solution	Concentration range (0.02%-0.2%); customizable adjuvants; irritant-free	$84+/month
Growth Booster Topicals	Vasodilation, anti-inflammatory action without DHT manipulation	Solution	Customizable combinations of minoxidil, tretinoin, caffeine, melatonin, and cetirizine	$54/month
OTC Support Products	Nutritional optimization, scalp environment enhancement, and daily follicular support	Serum, supplements, shampoo, and conditioner	Evidence-based supplements targeting TRT-specific deficiencies; irritant-free hair care products	$29+/month

Method #1: Oral Medications for Systemic Effects

Why Choose Oral Treatment?

This systemic approach provides several key advantages for men on testosterone therapy:

Benefit:	Details:
✓ Comprehensive treatment	Systemic DHT blocking plus vasodilation for growth stimulation
✓ Maximum potency	Up to 93% DHT reduction with dutasteride
✓ Convenience	Once-daily dosing
✓ Customizable	Combination options with growth stimulators

How Do Oral Medications Work to Treat Hair Loss?

DHT blockers like finasteride and dutasteride treat hair loss by suppressing the 5α-reductase enzymes that metabolize testosterone into DHT. Oral preparations have systemic effects and therefore offer extensive treatment. They can be used in conjunction with oral growth stimulators, such as minoxidil, to minimize hair loss associated with TRT. 

Finasteride inhibits the Type II 5α-reductase enzyme to reduce DHT levels by up to 70%. In contrast, dutasteride is a more potent intervention as a dual inhibitor of both Type I and Type II 5α-reductase enzymes, achieving up to 93% lower DHT levels. This thorough DHT suppression can make dutasteride useful for advanced hair loss cases as well as high-dose TRT patients who may not respond to topical treatments.^[12]Arif, T., Dorjay, K., Adil, M., Sami, M. (2017). Dutasteride in Androgenetic Alopecia: An Update. Current Clinical Pharmacology. 12(1). 31-35. Available at: … Continue reading 

Studies indicate that dutasteride’s therapeutic effects may continue to build beyond the 12 months at which many finasteride users experience a plateau, further establishing dutasteride as the most potent treatment option. While oral DHT blockers offer powerful treatment, their systemic effects contribute to a greater risk of serious side effects, so strict medical oversight is required.^[13]Harcha, W.G., Martinez, J.B., Tsai, T-F., Katsuoka, K., Kawashima, M., Tsuboi, R., Barnes, A., Ferron-Brady, G., Chetty, D. (2014). A randomized, active- and placebo-controlled study of the efficacy … Continue reading

Ulo’s Oral Medication Approach

Ulo’s oral treatments offer effective systemic intervention through various formulations designed for optimal bioavailability, featuring customizable options. Their oral Dutasteride Rx delivers a 0.5 mg dose of dual enzyme-blocking treatment in a softgel format designed to enhance absorption, overcoming the poor bioavailability of powder formulas touted by competitors.  

Their gentler oral Finasteride Rx also offers systemic DHT suppression in a once-daily capsule, while an oral Minoxidil Rx (1.25 mg or 2.5 mg) tablet formula increases systemic circulation and upregulates hair growth factors to treat hair loss as an alternative to DHT-blocking medications. 

Ulo also offers oral preparations that synergistically combine DHT blockers with minoxidil for effects that are shown to exceed those of monotherapies: Dutasteride + Minoxidil Rx and Finasteride + Minoxidil Rx, which come with optional adjuvants like vitamin D and folic acid to address deficiencies. Rather than combining oral dutasteride and minoxidil into a single capsule, as competitors do, Ulo maintains a separate soft gel and powder format for each, enabling proper absorption. 

Key Takeaway: Oral medications such as finasteride, dutasteride, and minoxidil provide the strongest systemic protection against hair loss during TRT, but their broad effects mean they require careful medical supervision to manage potential side effects.

Method #2: Topical Finasteride for Precision DHT Blocking

Why Choose Topical Finasteride?

Topical finasteride offers these strategic benefits for TRT patients:

Benefit:	Details:
✓ Targeted action	Scalp-focused DHT reduction
✓ Flexible dosing	Low-dose (0.005%) and full-strength (0.2%) options
✓ Safer alternative to oral	Comparable efficacy to oral without systemic exposure side effects
✓ Customizable	Optional minoxidil and adjuvant combinations

How Does Topical Finasteride Work?

Topical finasteride delivers targeted DHT suppression directly to the scalp, minimizing effects on the rest of the body. Studies show that topical finasteride can reduce scalp DHT to a therapeutic effect with little impact on serum DHT levels. In contrast, oral finasteride reduces DHT levels throughout the entire system. For men on TRT, maintaining systemic DHT is essential for bone, muscle, and sexual health; therefore, topical finasteride is typically the preferred option.^[14]Kinter KJ, Amraei R, Anekar AA. Biochemistry, Dihydrotestosterone. [Updated 2023 Jul 30]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: … Continue reading,^[15]Piraccini, B.M., Blume-Peytavi, U., Scarci, F., Jansat, J.M., Falques, M., Otero, R., Tamarit, M.L., Galvan, J., Tebbs, V., Massana, E. (2021). Efficacy and safety of topical finasteride spray … Continue reading

Topical formulations also allow more precise dosing with flexible concentrations that can be tailored to patient needs and responses. Low-dose formulas (0.005%) may be more appropriate for early-stage or moderate TRT patients, while higher-strength options (0.2%) can offer more aggressive treatment for substantial hair loss or intensive TRT protocols. Topical solutions can easily incorporate elective adjuvants, such as absorption enhancers and anti-inflammatories, for synergistic benefits.^[16]Kinter KJ, Amraei R, Anekar AA. Biochemistry, Dihydrotestosterone. [Updated 2023 Jul 30]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: … Continue reading

Ulo’s Topical Finasteride System

Ulo’s topical finasteride solution provides targeted scalp treatment with an optimized delivery base that is free from potential irritants, such as propylene glycol. Their fully customizable Finasteride + Minoxidil Plus Rx is available in finasteride doses of 0.005% for gentler therapy and 0.2% for stronger intervention. 

The robust formulation includes a wide range of synergistic add-on choices that address multiple hair loss pathways: up to 7% minoxidil for growth stimulation, tretinoin for better absorption, and multiple antioxidants for comprehensive support. This adaptability enables treatment tailored to patient needs rather than fixed protocols. Physician-crafted and supervised topical protocols are considered safe and effective for prolonged use to complement TRT journeys.

Key Takeaway: Topical finasteride allows TRT patients to lower scalp DHT while preserving systemic androgen function, making it a preferred option for balancing hair health with hormonal benefits.

Method #3: Topical Dutasteride for Comprehensive Scalp Protection

Why Choose Topical Dutasteride?

This powerful topical approach delivers distinct advantages:

Benefit:	Details:
✓ Dual enzyme blocking	Inhibits both Type I and Type II 5α-reductase
✓ Max scalp DHT reduction	Superior enzyme inhibition for aggressive protocol
✓ Safe and targeted treatment	Potent effects without systemic exposure
✓ Concentration control	Low-dose (0.02%) to full-strength (0.2%) options
✓ Personalized add-ons	Adjuvants can be tailored to individual needs

How Does Topical Dutasteride Work?

Topical dutasteride leverages the dual enzyme inhibition and localized efficacy discussed in Methods 1 and 2 to powerfully suppress scalp DHT levels while maintaining systemic DHT. This approach can be beneficial for patients on intensive TRT protocols that don’t respond to single-enzyme-blocking treatments. 

The superior targeted DHT suppression of topical dutasteride makes it an excellent choice for severe hair loss and TRT scenarios. It is the most potent topical DHT blocker available. Like topical finasteride, its concentration flexibility and easy incorporation of adjuvants enable more highly tailored and adaptable treatment compared to oral administration.^[17]Arif, T., Dorjay, K., Adil, M., Sami, M. (2017). Dutasteride in Androgenetic Alopecia: An Update. Current Clinical Pharmacology. 12(1). 31-35. Available at: … Continue reading,^[18]Harcha, W.G., Martinez, J.B., Tsai, T-F., Katsuoka, K., Kawashima, M., Tsuboi, R., Barnes, A., Ferron-Brady, G., Chetty, D. (2014). A randomized, active- and placebo-controlled study of the efficacy … Continue reading,^[19]Obeid, M., Fattah, N., Elfangary, M., & Husseni, R. (2024). Comparison between topical minoxidil 5% alone versus combined with dutasteride (topical 0.02% through microneedling or oral 0.5 mg) in … Continue reading

Ulo’s Topical Dutasteride Excellence

Ulo’s topical dutasteride offerings include both low-dose (0.02%) and full-strength (0.2%) versions of their Dutasteride + Minoxidil Plus Rx solution, delivering potent dual enzyme inhibition for precision scalp treatment. While the lower concentration may suit maintenance or preventative protocols, the highly concentrated formula may benefit severe hair loss patients and aggressive TRT regimens. 

Like Ulo’s topical finasteride products, their dutasteride selections are fully customizable with synergistic add-ons that include minoxidil (up to 7%), caffeine, tretinoin, cetirizine, and melatonin. The clinically backed formulas are designed to deeply penetrate the scalp and follicles without the use of irritants, corticosteroids, or unproven ingredients seen in competing premium brands. 

The platform’s Build Your Own Topical feature offers complete customization across the full range of topical electives, including a choice of finasteride or dutasteride with individualized adjuvant combinations. 

Key Takeaway: Topical dutasteride delivers the most powerful scalp-targeted DHT reduction available and is well-suited for men with significant hair loss or intensive TRT regimens that do not respond to other approaches.

Method #4: Growth Booster Topicals for Non-Hormonal Treatment

Why Choose Growth Booster Topicals?

Non-hormonal growth stimulation provides these unique benefits:

Benefit:	Details:
✓ Hormone-free treatment	Growth stimulation without hormonal manipulation
✓ Anti-inflammatory	Addresses scalp inflammation contributing to hair loss
✓ High-strength formulas	7% minoxidil with absorption enhancers
✓ Versatile use	Standalone or in combination with DHT blockers

How Do Growth Booster Topicals Work?

Growth stimulators are useful for comprehensive hair restoration during TRT to address non-hormonal hair loss pathways outside of DHT’s purview. Minoxidil is one of the most commonly used medications, acting as a vasodilator to boost scalp circulation while upregulating growth factors to extend the anagen phase of each hair cycle.^[20]Obeid, M., Fattah, N., Elfangary, M., & Husseni, R. (2024). Comparison between topical minoxidil 5% alone versus combined with dutasteride (topical 0.02% through microneedling or oral 0.5 mg) in … Continue reading,^[21]Koralewicz, M.M., Szatkowska, O.A. (2024). Topical solutions for androgenetic alopecia: evaluating efficacy and safety. Forum Dermatologicum. 10(3). 71-78. Available at: … Continue reading

Calming agents like cetirizine, melatonin, and caffeine address scalp inflammation, another key contributor to follicular damage and hair loss. Caffeine also enhances follicular nutrient supply to act as a growth stimulant, while melatonin’s antioxidant protection reduces shedding.^[22]Koralewicz, M.M., Szatkowska, O.A. (2024). Topical solutions for androgenetic alopecia: evaluating efficacy and safety. Forum Dermatologicum. 10(3). 71-78. Available at: … Continue reading

The powerful combination of growth stimulation with anti-inflammatory action can provide standalone benefits or be applied as a complementary therapy with DHT blockers. Studies show that minoxidil is effectively combined with DHT blockers, offering greater outcomes than single-agent therapies. Growth boosters are therefore vital to the success of TRT hair loss prevention protocols.^[23]Obeid, M., Fattah, N., Elfangary, M., & Husseni, R. (2024). Comparison between topical minoxidil 5% alone versus combined with dutasteride (topical 0.02% through microneedling or oral 0.5 mg) in … Continue reading,^[24]Koralewicz, M.M., Szatkowska, O.A. (2024). Topical solutions for androgenetic alopecia: evaluating efficacy and safety. Forum Dermatologicum. 10(3). 71-78. Available at: … Continue reading

Ulo’s Growth Booster Solutions

Ulo offers two customizable growth stimulation topicals that can be used alone or in conjunction with DHT blockers, depending on the prescribed protocol. Their Minoxidil + Tretinoin Plus Rx solution features a high 7% minoxidil in combination with tretinoin for optimal absorption. Adjuvants like cetirizine, melatonin, and caffeine may be added for anti-inflammatory support, antioxidant protection, and enhanced microcirculation. 

For patients interested in calming the scalp without actives like minoxidil, the Cetirizine Plus Rx solution delivers a proven dose of 1% cetirizine. This potent anti-inflammatory also has anti-histamine properties to support scalp health and hair growth. Caffeine and melatonin may be added for well-rounded, non-hormonal treatment. 

Like all Ulo topicals, these selections offer superior scalp penetration without irritating carriers or excipients, making them ideal for extended daily use in patients with sensitive skin or long-term combination therapy needs. 

Key Takeaway: Growth booster topicals like minoxidil, caffeine, and melatonin support follicle strength through circulation, inflammation control, and antioxidant activity, and they can be used alone or combined with DHT blockers for greater results.

Method #5: OTC Support Products for Foundational Care

Why Choose Premium OTC Products?

Quality over-the-counter support offers these foundational advantages:

Benefit:	Details:
✓ Nutritional support	Addresses deficiencies contributing to hair loss
✓ Scalp optimization	Creates an ideal environment for treatment absorption
✓ Natural ingredients	Active botanicals and peptides
✓ Complete system	Serum, supplements, shampoo, and conditioner

How Do OTC Products Work?

High-quality, non-prescription products can also help target underlying hair health factors without hormonal suppression. These include nutritional support formulas that help address common deficiencies linked to hair loss. Such formulas may contain active botanical agents with anti-inflammatory or growth-promoting effects, providing gentle systemic support.^[25]Koralewicz, M.M., Szatkowska, O.A. (2024). Topical solutions for androgenetic alopecia: evaluating efficacy and safety. Forum Dermatologicum. 10(3). 71-78. Available at: … Continue reading

Specialty hair care products, such as shampoos, conditioners, and serums, nourish and balance the scalp, providing an optimal environment for prescription medications to take hold and support overall treatment objectives. Non-prescription hair growth serums may contain botanical extracts and peptide-based therapeutics that soothe and strengthen the follicles as a complement to medical protocols. 

Ulo’s OTC Support Range

Ulo’s four non-prescription haircare products support foundational hair health in synergy with the brand’s extensive prescription range. Their Hair Growth Serum contains three proprietary peptide blends that demonstrated comparable efficacy to minoxidil in a medically supervised study. Natural active ingredients such as saw palmetto, rosemary oil, and adenosine provide gentle DHT suppression, enhanced circulation, and growth stimulation, respectively.

The nutritional Hair Growth Supplement provides extensive hair and scalp nourishment with proven ingredients like vitamin D, biotin, hydrolyzed fish collagen, and saw palmetto. Antioxidants such as chlorophyll and astaxanthin combat oxidative stress from within. 

Lastly, the Thickening Shampoo and Conditioner provide gentle daily scalp optimization with natural actives like caffeine to boost circulation, keratin to strengthen strands, and saw palmetto to suppress DHT levels. The PhD scientist-crafted formulas are free of known irritants and artificial fragrances, made instead with nourishing oils and amino acids that encourage natural hair growth and work to improve prescription treatment response.

Key Takeaway: Over-the-counter serums, supplements, and hair care products build the foundation for long-term hair preservation by supporting scalp health, addressing nutritional needs, and enhancing the effects of prescription treatments.

Why Ulo Stands Out for TRT Patients

Managing hair health during TRT requires clinical expertise to address unique hormonal challenges that generic treatments often miss. Ulo’s multidisciplinary care, personalized protocols, advanced formulations, and high-quality standards make it a leader in TRT-focused hair restoration telehealth. Below is a summary of what sets Ulo apart.

✓ Comprehensive Medical Oversight

Ulo partners exclusively with licensed and board-certified physicians to provide safe and effective care that meets the highest regulatory and safety standards. Full medical consultations and evaluations at onboarding enable Ulo’s qualified doctors to craft tailored treatment plans, while ongoing monitoring protocols establish positive outcomes.

✓ Dual Expertise in TRT and Hair Loss

Ulo operates as a leading telehealth provider with state-of-the-art services in both hair restoration and TRT, employing physicians with experience in both areas. The specialists at Ulo are uniquely qualified to address TRT-related hair loss with practical insights and actionable solutions.

✓ True Customization for TRT Needs

While most competitors tout fixed, one-size-fits-all formulations, Ulo, in contrast, carries truly customizable treatment options with adjustable doses and elective add-ons to meet individual patient needs. This is an important feature for TRT patients, who may require medications that vary from standard formulas and can be adjusted to changing responses over time.

✓ Pharmaceutical-Grade Quality Standards

Ulo ensures product quality by sourcing all medications from certified domestic pharmacies. Formulations are designed for peak bioavailability with innovative delivery systems, free of harsh additives like propylene glycol, which can be found in many hair loss products. 

✓ Transparent Pricing and Customer Support

Ulo’s fixed-rate monthly subscription pricing avoids the rising costs and hidden fees that are common among telemedicine competitors. This allows patients to budget for long-term integrated care. Subscriptions cover all essential services, including physician consultations, follow-ups, prescription deliveries, and more. The platform’s responsive customer service ensures uninterrupted treatment and full support throughout the process.

Ulo vs. Standard Hair Loss Providers

The chart below illustrates the main differences between Ulo’s expert model and standard telehealth hair loss providers, showcasing how Ulo is uniquely equipped to meet the hair restoration needs of TRT patients.

Feature	Ulo	Standard Providers
Medical Oversight	Board-certified physicians with TRT and hair loss expertise	Generic telehealth consultations
Customization	True concentration flexibility (0.005%-0.2%); adjuvant options	Fixed formulations; limited options
Formulation Quality	Pharmaceutical-grade; soft gel dutasteride for optimal bioavailability	Standard compounding; limited bioavailability
Ingredient Safety	Irritant-free; no propylene glycol or corticosteroids	Often contains propylene glycol and harsh excipients
TRT Knowledge	Dual expertise in hormone optimization and hair restoration	Hair loss focus only; limited TRT understanding
Pricing Model	Transparent flat-rate monthly subscriptions	Hidden fees and escalating costs are common
Quality Assurance	Certificates of analysis; FDA-approved pharmacy sourcing	Limited transparency; variable quality standards
Combination Options	Extensive adjuvant library (tretinoin, caffeine, melatonin, cetirizine)	Basic combinations; limited synergistic ingredients
Follow-up Care	Unlimited physician access; regular monitoring protocols	Limited follow-up; basic customer service
Treatment Coordination	Can coordinate with existing TRT protocols	No hormone therapy coordination

Safety Considerations

Hair restoration therapies, especially hormonal medications like DHT blockers, can interact with TRT and require strict medical oversight to monitor for adverse reactions. Among the different treatment methods discussed, safety profiles vary. Here is a brief overview of their safety findings. All medical concerns should ultimately be discussed with a qualified clinician.

Prescription treatments display differing safety profiles based on the delivery method, whether oral or topical. Oral DHT blockers have systemic exposure and therefore carry the risk of systemic side effects like sexual dysfunction, mood disorders, and gynecomastia; all of which require prompt medical evaluation. Oral minoxidil requires cardiovascular monitoring due to its circulatory effects.

Topical DHT blockers have limited systemic exposure and therefore milder associated side effects, often no more than minor localized scalp irritation that tends to resolve within 2-4 weeks. Regular follow-up exams are required every 3-6 months during the first year of prescribed hair loss treatment.

Over-the-counter products, such as shampoos and nutritional supplements, carry minimal risk; however, patients with allergies or sensitivities should carefully read the ingredients before use. OTC treatments can sometimes interact with medications or exacerbate underlying conditions, so it’s best to consult a healthcare professional for guidance. 

Contraindications for prescription DHT blockers include severe cardiovascular conditions, active scalp infections, and liver disease. Women who are pregnant or plan to have a future pregnancy should avoid DHT blockers due to possible birth defects. 

Consult your doctor for a complete list of all possible side effects, contraindications, and risk mitigation strategies. 

Conclusion: Battling the Hair vs. Health Trade-Off

Accelerated hair loss can be one of the most frustrating and disruptive elements of TRT, calling for sophisticated approaches that go beyond conventional hair loss treatment. TRT creates unique challenges that demand advanced intervention strategies.

Thanks to the wide-ranging methods discussed in this guide, men no longer have to choose between hair preservation and hormone optimization on TRT. With dual expertise, qualified medical oversight, and tailored formulations that meet leading quality standards, Ulo rises to meet the varied needs of TRT patients where generic providers fall short.

Don’t allow hair loss to interfere with your journey to hormonal health and restored vitality. Ulo’s scientific approach and clinical experience make them the clear choice for men seeking to maintain their hair while optimizing their hormone therapy. Consult with a licensed Ulo physician today to craft a personalized treatment plan.

Discover your unique hair preservation strategy with Ulo.

Frequently Asked Questions

Does Ulo offer testosterone replacement therapy? 

Yes, Ulo has testosterone replacement therapy offerings that include injections, topicals, and oral preparations. Like Ulo’s hair restoration services, their TRT program is medically rigorous and tailored to individual needs. Ulo’s multidisciplinary expertise gives them unique insight, enabling them to properly address both sides of the hormone equation when treating TRT-related hair loss.

Should I discuss hair loss concerns and treatment options with my doctor when starting TRT? 

Yes, all hair concerns should be discussed with your clinician before starting TRT to enable proactive treatment planning and fully informed care decisions. Your doctor will assess your health profile and treatment goals to decide whether hair loss intervention is an appropriate choice and, if so, which method is best for you. 

Which hair loss treatments require a prescription? 

Prescriptions are required for DHT blockers like dutasteride and finasteride, growth stimulators like minoxidil, and some customized topicals. All require proper diagnostic and follow-up care protocols that meet clinical safety standards. Options that don’t require a prescription include over-the-counter nutritional supplements, serums, shampoos, and conditioners with unrestricted active ingredients like botanical extracts and peptides.   

Can I combine hair loss treatment methods? 

Yes, some hair loss treatments can be combined for synergistic effects. Popular combinations include minoxidil with DHT blockers (dutasteride or finasteride), alongside nutritional support. Treatments should only be combined under close medical supervision to avoid harmful interactions.

When do most hair loss treatments show results? 

Although results differ depending on the patient and treatment type, most users experience initial effects within the first 3-6 months and more substantial benefits over 6-18 months. Consistent daily administration is required to successfully achieve and maintain hair loss treatment benefits. 

What are common hair loss treatment side effects? 

Potential side effects vary based on the type of treatment and are usually controllable with the right medical care. Topical treatments can produce mild and temporary irritation at the application site.  Although rare, oral DHT-blocking medications can lead to systemic side effects like sexual dysfunction and mood disturbances requiring immediate medical attention. Thoroughly discuss all potential side effects and suitable monitoring protocols with your provider.

How much do Ulo’s hair loss treatments typically cost? 

Ulo’s price points vary by treatment type and level of customization. Pricing reflects flat-rate monthly subscription fees that not only cover the cost of the medication but also include essential telehealth services like doctor consultations, follow-ups, and prescription deliveries. Their prescription oral treatments range from $24 to $65 per month, while topicals range from about $49 to $94 per month. OTC support products start at $29 per month. 

What should I expect during my first consultation with Ulo? 

The Ulo onboarding process starts with a thorough medical intake form that covers your health profile, treatment goals, and current medications. You will be partnered with one of Ulo’s licensed physicians, who, after reviewing your information, will collaborate with you to design a treatment plan tailored to your specific needs. During the initial consultation, your doctor will thoroughly discuss treatment options, realistic expectations, safety, and follow-up protocols to guarantee safe and effective care.