What is fibrosis? It's another term for "excess collagen". It's when our bodies over-accumulate connective tissue as a response to inflammation. In advanced stages, fibrosis leaves the skin shiny and oily-looking. And in balding scalps, fibrosis is technically known as "perifollicular fibrosis" -- or fibrotic tissue encircling each hair follicle.
We know from heart disease research that fibrosis inhibits blood, oxygen, and nutrient flow... but by how much? Well, research shows that balding scalp skin has just 60% the oxygen levels of hair-bearing scalp skin. Without proper blood, oxygen and nutrient flow -- hair follicles cannot survive.
What is calcification? It's the abnormal deposition of calcium in our joints, tendons, soft tissues, and even capillary networks. And believe it or not, calcification was first medically documented in balding scalps over 70 years ago.
Dr. Frederick Hoelzel wrote about a connection with calcification, restricted blood flow, and baldness while studying cadavers. He discovered that balding regions lined up to places where the scalp was completely calcified:
“Baldness occurred in persons in whom calcification of the skull bones apparently had not only firmly knitted the cranial sutures but also closed or narrowed various small foramens through which blood vessels pass most prominently in persons with a luxuriant crop of hair.”
In other words, the blood vessels supporting the hair follicles were calcified in thinning regions, so that less blood, oxygen, and nutrients could reach those follicles. The end-result: hair miniaturization, and then baldness.