Rob English 
CRABP2 is one of two genes found within the CRABP family alongside CRABP1. CRABP2 is a key regulator of retinoic acid, a vitamin A derivative, transporting it around the cell and helping its metabolism. Both CRABP2 and retinoic acid have been suggested in the literature to have roles in the maintenance of hair health. This … Read more…
BTD encodes the protein biotinidase, an enzyme crucial for biotin use throughout the human body. Biotin, or vitamin B7, is an essential nutrient that must be acquired from the diet. Biotin has been shown to have a range of biological functions, including a role in maintaining hair health. BTD polymorphisms can lead to a failure … Read more…
CYP19A1 is a gene within the cytochrome P450 superfamily, a large network of genes that regulate various critical processes throughout the body. CYP19A1 encodes the protein aromatase, which is involved in the conversion of androgens, such as testosterone, into estrogens. Aromatase is believed to play a key role in regulating hair growth, and several studies … Read more…
COL1A1 is a gene within the collagen superfamily, a large network that comprises at least 44 genes and 28 proteins. The collagen proteins have a variety of roles, with perhaps their most crucial being to support the structure of tissues throughout the body. COL1A1 and COL1A2 produce the protein chains that combine to form type … Read more…
2dDR Hair is a company that sells two hair care products: 2DDR+ Advanced Topical Hair Formula and Generic Deoxyribose 2dDR. The website features product prices and a page dedicated to a recent mouse study that has been published about the main ingredient, 2-deoxy-D-ribose (2dDR). 2dDR is a naturally occurring sugar in the human body with … Read more…
Angiotensin-converting enzyme facilitates the conversion of angiotensin I to angiotensin II. This, alongside the degradation of bradykinin, leads to vasoconstriction (the tightening of blood vessels). As hair follicles require an adequate supply of blood for growth and health, it is thought that increased ACE activity can contribute to hair loss. In this article, we will … Read more…
The NR3C1 gene encodes the glucocorticoid receptor, which is essential for mediating the effects of glucocorticoids in various physiological processes, including metabolism, immune response, and stress regulation. This receptor plays a critical role in the body’s ability to respond to glucocorticoid medications, making it a key factor in conditions treated with these drugs. This article … Read more…
The PGFTR gene encodes the prostaglandin F2 alpha (PGF2α) receptor, a critical component in various physiological processes. PGFTR is particularly significant in the context of hair loss due to its involvement in hair follicle and melanocyte growth. Studies have shown that PGF2α and its analogs, such as latanoprost, can stimulate hair growth and treat eyelash … Read more…
The PTGES2 gene encodes the enzyme prostaglandin E synthase 2, which plays a crucial role in converting prostaglandin H2 to prostaglandin E2 (PGE2). This enzyme is significant in various physiological processes, including inflammation and hair growth. Notably, studies have identified higher levels of PGE2 in non-balding scalps compared to balding ones, highlighting the potential relevance … Read more…
IGF1R is a receptor within the IGF gene family, a large network of genes that work together to regulate various processes. IGF1R mediates the effects of IGF-1, another gene within the family that is believed to be important in hair growth. Studies have shown that IGF-1 regulates key aspects of hair growth, and having low … Read more…